Citalopram is a selective serotonin reuptake inhibitor used primarily as an antidepressant. It works by blocking the serotonin transporter, thereby increasing serotonin levels in the synaptic cleft. The elevated serotonin enhances stimulation of postsynaptic receptors, which contributes to mood regulation over time. The medication is absorbed orally, reaches peak plasma concentration within a few hours, and is metabolized mainly by the liver. Elimination occurs through renal excretion and a modest half-life of about 35 hours, leading to steady-state levels after several weeks. The primary therapeutic effect results from sustained serotonergic activity that improves depressive symptoms.

Citalopram is a selective serotonin reuptake inhibitor used to treat depression and related conditions. It works by blocking the reabsorption of serotonin in the brain, increasing the amount of this neurotransmitter available to neurons. This elevation of serotonin helps improve mood and reduce anxiety over time. The drug is absorbed orally and metabolized primarily by the liver enzyme cyp2c19, producing an active metabolite that contributes to its effect. It has a long elimination half-life, allowing once-daily dosing and steady blood levels. The medication selectively targets the serotonin transporter, which limits its action to the serotonergic system while sparing other neurotransmitters. Patients typically experience symptom relief after several weeks as brain chemistry adjusts to the increased serotonin. Overall Citalopram acts as a pharmacologic agent that modulates mood regulation through selective serotonin reuptake inhibition.

Citalopram may cause nausea and dizziness in some patients. It can also lead to insomnia or excessive sleepiness depending on the individual. Fatigue and dry mouth are common complaints reported during treatment. Changes in weight may occur and some users experience sexual dysfunction. Headaches and mild tremor have been observed in a portion of patients. Gastrointestinal disturbances such as diarrhea or constipation can appear. These effects often diminish as the body adjusts to the medication.

Citalopram is a selective serotonin reuptake inhibitor commonly prescribed for depression and anxiety disorders. Common side effects include nausea, dry mouth, excessive sweating, and drowsiness. Some individuals may experience dizziness, blurred vision, or tremors, especially when standing up quickly. Weight changes, such as mild loss or gain, are occasionally reported but not universally observed. Rare but serious reactions can involve cardiac arrhythmias, particularly at higher doses or in patients with preexisting heart conditions. Sexual dysfunction, including decreased libido or difficulty achieving orgasm, has been documented in some users. Most side effects diminish over time as the body adjusts to the medication.