Domperidone is a medication that blocks dopamine receptors in the gastrointestinal tract. It is prescribed to relieve nausea and vomiting by stimulating gastric emptying. The active ingredient increases the strength of stomach and intestinal muscle contractions. This heightened activity speeds the passage of food through the digestive system. As a result the sensation of nausea is reduced and patient comfort improves. The drug also helps prevent delayed stomach emptying associated with gastroparesis. It acts selectively on peripheral dopamine receptors without significant central effects. The overall increase in gastrointestinal motility produces the therapeutic benefit of the medication.

Domperidone is a prescription medication that works in the gastrointestinal tract. It blocks dopamine d2 receptors in the stomach and intestines. This inhibition increases the contractions of the digestive muscles. As a result food moves through the gut more quickly and empties from the stomach faster. The drug also acts on the brain's chemoreceptor trigger zone to stop nausea signals. Patients therefore experience less nausea and vomiting. Overall it is used to improve gastric emptying and relieve discomfort associated with delayed stomach movement.

Domperidone can cause dry mouth. It may lead to drowsiness. Some users report headaches. Less commonly it can affect heart rhythm. There is a risk of extrapyramidal symptoms. Constipation or diarrhea have been noted. Swelling in the hands or feet may occur. Severe allergic reactions such as rash or breathing difficulty are rare.

Domperidone is a medication used to treat nausea and vomiting by enhancing gastrointestinal motility. Some users may experience headaches or dizziness as a result of its effect on the central nervous system. It can also cause dry mouth or mild abdominal discomfort in certain individuals. Rarely, changes in heart rhythm have been reported, especially at higher doses or when combined with other drugs. Some people notice swelling of the ankles or sudden weight gain due to fluid retention. It may interact with medications that affect the qt interval, potentially increasing cardiac risk. Exposure to excessive sun or heat is sometimes reported because the drug can affect sweating patterns.