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Generic Adalat ( Nifedipine )
Adalat
| Active ingredient | Nifedipine |
|---|---|
| Mechanism of action | Calcium-channel blocker that relaxes vascular smooth muscle |
| Common dose | Typically 10 mg-20 mg once daily (adjustable per patient) |
| What is it used for? | Treatment of hypertension and stable angina pectoris |
| Important information on taking | Take with or without food; swallow whole - do not crush or chew |
| Common side effects | Headache, flushing, dizziness, peripheral edema |
| Serious risks | Hypotension, myocardial infarction, hepatic dysfunction |
| Interactions | May increase levels of cyclosporine, lithium, and certain CYP3A4 substrates; avoid concurrent strong CYP3A4 inhibitors |
| Contraindications | Hypersensitivity to nifedipine or any component of the formulation |
| Legal status | Prescription-only medicinal product (Rx) |
Exploring the basics of Adalat
What is Adalat and how does it work?
Adalat is a medication that contains the active ingredient nifedipine and is classified as a dihydropyridine calcium-channel blocker. This drug is used primarily to treat hypertension and to relieve chronic stable angina by reducing arterial resistance. Nifedipine works by binding to l-type voltage-gated calcium channels on vascular smooth muscle cells. This binding prevents calcium influx, leading to relaxation of arterial walls and a consequent decrease in peripheral vascular resistance. The resulting reduction in systemic vascular resistance lowers blood pressure, while the modest reduction in cardiac workload improves oxygen delivery. Pharmacodynamically the agent acts as a reversible antagonist of calcium channels, producing a rapid onset of effect that peaks within one to two hours after oral administration. The eliminated drug is metabolized mainly by the hepatic enzyme cyp3a4 into inactive metabolites that are excreted renally.
Pharmacological properties of Adalat
Adalat is a brand name for nifedipine, a calcium channel blocker used to treat high blood pressure. It works by relaxing blood vessels, which lowers resistance to blood flow. The drug blocks l-type calcium channels in vascular smooth muscle. This inhibition prevents calcium influx, reducing muscle contraction. As a result, arterial walls relax and blood pressure decreases. Its selective action on peripheral vessels provides effective antihypertensive effect without significant impact on heart rate.
Therapeutic uses of Adalat
| Heart failure | Typical dose: 5 mg twice daily for 6-12 weeks |
|---|---|
| Angina pectoris | Typical dose: 5 mg once daily for at least 12 weeks |
| Acute myocardial infarction | Typical dose: 5 mg three times daily for 3-6 months |
Common side effects of Adalat
Common reactions Adalat can cause
Adalat may cause dizziness in some patients. It can also lead to headaches as a frequent side effect. Some individuals experience swelling of the feet or ankles. Fatigue is reported by a number of users during treatment. Occasional nausea or mild stomach discomfort may occur. Rarely, liver enzymes can be elevated, requiring monitoring. Skin rashes or itching have been documented in certain cases.
What to know before starting Adalat
Adalat may cause dizziness or light-headedness in some patients. It can also lead to headache or flushing of the skin. Swelling of the ankles or lower legs is another reported effect. Some individuals experience rapid or irregular heartbeat. Nausea or abdominal discomfort may occur occasionally. Rarely, the medication can cause shortness of breath or chest discomfort. These reactions are generally mild and do not require immediate medical attention.
Frequently observed responses to Adalat
- Headache
- Dizziness
- Nausea
- Fatigue
- Swelling of ankles
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| Shipping method | Delivery time | Price | |
| Airmail service Delivery | 14-21 days | 10$ | Tracking# available in 4 days |
| Trackable service Delivery | 9-14 days | 30$ | Tracking# available in 2 days |
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