Aciclovir is an antiviral medication that targets viral dna polymerase. It is used to treat infections caused by herpes simplex viruses. The drug is converted intracellularly into a triphosphate metabolite that inhibits viral dna synthesis. This inhibition prevents viral replication and spread to adjacent cells. Aciclovir selectively affects infected cells while sparing uninfected host cells. Its therapeutic effect is achieved through selective activation in virally infected cells leading to chain termination of viral dna elongation.

Aciclovir is an antiviral medication used to treat infections caused by herpes simplex viruses. It works by being phosphorylated by viral thymidine kinase to form Aciclovir triphosphate, which then inhibits viral dna polymerase. This inhibition prevents the synthesis of viral dna, leading to termination of viral replication. The drug selectively targets infected cells while sparing uninfected host cells due to the dependency on viral kinase for activation. Clinically it is employed to reduce the duration and severity of genital herpes outbreaks and to manage chickenpox lesions. Its pharmacokinetic profile includes rapid oral absorption, extensive distribution, and renal excretion of unchanged drug.

Aciclovir may cause mild nausea or headache in some patients. Skin rash can appear as a rare reaction. Adjustments in dosage are sometimes needed for patients with kidney impairment. Neurological symptoms such as dizziness or confusion are uncommon but reported. Some individuals experience increased liver enzyme levels detected by blood tests. Most side effects are transient and do not require treatment. Serious allergic reactions are very rare.

Aciclovir is an antiviral medication used to treat viral infections. Common side effects include headache and nausea. Some patients may experience dizziness or fatigue. Skin reactions such as rash or itching can occur. In rare cases, visual disturbances have been reported. Laboratory abnormalities like elevated liver enzymes may be observed. These effects are generally mild and transient. Most individuals tolerate the drug without serious complications.