Nizoral is an antifungal medication whose active ingredient is ketoconazole. It is formulated for topical and oral use to treat fungal infections of the skin and mucous membranes. Therapeutically it aims to eliminate superficial mycoses such as athlete's foot ringworm and candidiasis. The drug works by inhibiting the fungal enzyme lanosterol 14a-demethylase which blocks ergosterol production. This disruption impairs the cell membrane leading to fungal growth arrest and death. The result is a reduction of infection symptoms and clearance of the organism from the treated area.

Nizoral is an antifungal medication used to treat skin and scalp infections. It works by inhibiting the fungal enzyme lanosterol 14-alpha-demethylase, which blocks the synthesis of ergosterol, a key component of fungal cell membranes. Without ergosterol the membrane becomes unstable, leading to fungal cell death. The drug is formulated as a cream, shampoo, and oral solution for topical or systemic use. Its pharmacodynamic effect results from selective binding to fungal sterol biosynthesis enzymes, sparing human cholesterol production. This targeted mechanism provides therapeutic action against dermatophytes and yeast infections.

Nizoral may cause mild skin irritation in some users. It can lead to dryness or flaking of the scalp. Occasionally users report a burning sensation after application. Rarely there are reports of mild allergy such as itching or rash. It may interact with certain shampoos that contain strong detergents. These effects typically resolve once the treatment stops.

Nizoral can cause skin irritation in some users. It may lead to itching or rash on the treated area. Some people experience dryness or peeling of the skin. The product can occasionally cause a mild burning sensation upon application. In rare cases it may trigger an allergic reaction with swelling or redness. Headache or dizziness has been reported in a small number of users. Changes in taste sensation have also been documented in isolated instances.