Arava is a disease-modifying antirheumatic drug indicated for the treatment of rheumatoid arthritis. It is formulated as an oral tablet that is taken once daily. The medication works by inhibiting the enzyme dihydroorotate dehydrogenase, which blocks the synthesis of pyrimidine bases. This inhibition reduces the proliferation of activated t lymphocytes. The resulting immunosuppression dampens the inflammatory response that damages joints. By decreasing immune cell activity, Arava helps lower disease activity and slow joint damage progression. Its therapeutic effect is observed after several weeks of consistent dosing. The drug does not cure rheumatoid arthritis but provides symptomatic and disease-modifying benefits.

Arava is a prescription drug indicated for the treatment of rheumatoid arthritis. It works by inhibiting an enzyme needed for pyrimidine synthesis in immune cells. The inhibition reduces the production of dna and rna in activated lymphocytes. This limits the cells' ability to proliferate and cause joint inflammation. The active metabolite of Arava suppresses inflammatory signaling pathways. By decreasing immune cell activity the medication helps preserve joint function. Pharmacokinetically the drug is absorbed orally and distributed to sites of inflammation. Its effect builds up gradually over several weeks as immune cell counts decline.

Arava may cause diarrhea that can range from mild to severe. Some patients experience nausea and abdominal discomfort. Liver enzyme elevations are possible and may affect liver function tests. Skin reactions such as rash or itching can occur. Hair thinning or loss has been reported in a small number of users. The medication can increase susceptibility to infections due to its effect on the immune system.

Arava is a medication used to treat rheumatoid arthritis and other inflammatory conditions. Common side effects may include diarrhea and mild stomach discomfort. Some people experience skin rash or itching as a reaction to the drug. Liver function tests are sometimes monitored because the medication can affect hepatic enzyme levels. Hair thinning or loss has been reported in a minority of users. Fatigue and headache are also occasionally observed during treatment.