For parenteral use Regional arterial perfusion is indicated for: localized melanoma of the extremities; localized sarcoma of the soft tissues of the extremities. neuroblastoma in children. For oral administration It is indicated for: multiple myeloma; widespread ovarian adenocarcinoma. Can be used for: breast carcinoma; polycythemia vera. Indications: Malignant melanoma of the skin, Malignant neoplasm of peripheral nerves and autonomic nervous system, Malignant neoplasm of the connective and soft tissues of the upper limb, Malignant neoplasm of the connective and soft tissues of the lower extremity, Malignant neoplasm of the breast, Malignant neoplasm of the ovary, Multiple myeloma, Polycythemia.